Alzheimer's Could Be A White Matter Disease, Not Gray Alzheimer’s Could Be A White Matter Disease, Not Gray Authored by RJ Tesi via RealClearScience, Alzheimer’s disease (Alzheimer’s) is conceptualized as a progressive consequence of two hallmark pathological changes in gray matter, in particular, extracellular amyloid plaques and neurofibrillary tangles. However, over the past several years, …